Benefits of Antihypertensive Pharmacologic Therapy and Blood Pressure Reduction in Outcome Trials
نویسندگان
چکیده
منابع مشابه
Ambulatory blood pressure monitoring in clinical trials with antihypertensive agents.
Ambulatory blood pressure monitoring (ABPM) is being used increasingly for the evaluation of antihypertensive agents in clinical trials. In this brief review several aspects of ABPM are discussed. In particular, attention is paid to the extent to which ABPM is subject to a placebo response and the extent to which the sample size of the study population can be reduced with this type of measureme...
متن کاملPharmacoeconomic benefits of antihypertensive therapy.
BACKGROUND Effective blood pressure reduction reduces cardiovascular risk and prevents later complications. OBJECTIVE To consider the pharmacoeconomic benefits of antihypertensive therapy. SUMMARY Every managed care pharmacist should consider the balance of cost and benefit of antihypertensive therapies, ensuring that best treatment options for patients with the lowest cost to the health ca...
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Timing of Antihypertensive Therapy and Circadian Blood Pressure Pattern To the Editor: We read with great interest the recent article by de la Sierra et al1 about the prevalence and factors associated with circadian blood pressure patterns in a huge population of 42 947 hypertensive patients studied with 24-hour ambulatory blood pressure monitoring. Their cross-sectional study shows an associat...
متن کاملAntihypertensive Drug Therapy in Consideration of Circadian Blood Pressure Variation*
J-MUBA was a large-scale clinical study which, for the first time in the world, evaluated the effects of an antihypertensive drug on circadian BP variation in more than 600 patients with hypertension. Although ACE inhibitors reportedly exert equal 24-hour antihypertensive effects on daytime and nighttime BP, and -blockers are reported to have weaker effects on nighttime BP than on daytime BP. H...
متن کاملCentral blood pressure measurements and antihypertensive therapy: a consensus document.
The 2003 European Society of Hypertension/European Society of Cardiology guidelines for the management of arterial hypertension1 included 2 important novel recommendations: assessment of the total cardiovascular risk should be taken into account in the management of the hypertensive patient, and quantification of risk should include subclinical target organ damage. These guidelines acknowledged...
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ژورنال
عنوان ژورنال: The Journal of Clinical Hypertension
سال: 2003
ISSN: 1524-6175,1751-7176
DOI: 10.1111/j.1524-6175.2003.01307.x